Advancing models of lung health and disease through interdisciplinary collaborations.
Nov 12, 2021
2:30PM to 3:30PM
Date(s) - 12/11/2021
2:30 pm - 3:30 pm
In vitro model systems of lung health and disease have historically been static – with no mechanical forces imposed on cells or tissues. This is in stark contrast to the human lung which stretches in and out each day to exchange over 10000 litres of air. What are we missing in conventional static in vitro model systems? Is there a way to integrate relevant mechanical forces into in vitro models? What role does tissue engineering and 3D bioprinting play in advancing static models to dynamic systems? This talk will overview the interdisciplinary efforts of the Tissue Engineering for Advanced Medicine (TEAM) Lab that are focused on pushing forward models to more accurately reflect the living, breathing lung. The talk will describe established and evolving methods for introduction of airflow, stretch, and 3D microenvironments.
Dr. Jeremy “Jay” Hirota obtained his BSc and PhD from McMaster University in Physiology and Pharmacology at the Firestone Institute for Respiratory Health followed by Post-doctoral work at the University of British Columbia at the James Hogg Research Centre and Vancouver Coastal Health Research Institute. An international training with Professor Philip Hansbro at the University of Newcastle (Australia) immediately preceded transition to faculty at UBC in 2015. In late 2016, Dr. Hirota returned “home” to McMaster University where he is the Canada Research Chair in Respiratory Mucosal Immunology with Adjunct Professor appointments at UBC and University of Waterloo. Dr. Hirota has a broad interdisciplinary program focused on cell biology, tissue engineering, biomedical engineering, bioinformatics, and translational lung research – all merging on mucosal immunity. Dr. Hirota is Co-Director of Molecular Phenotyping and Imaging Core with Dr. Ask. Dr. Hirota is also Co-Founder and CEO of Infinotype, a software as a service solutions company focused on health informatics and molecular phenotyping.