Engineering Biomaterials to Mimic and Repair Tissues
Nov 26, 2021
2:30PM to 3:30PM
Date(s) - 26/11/2021
2:30 pm - 3:30 pm
The promise of tissue engineering is to repair and even substitute native tissues with artificial counterparts. Despite much progress in the field, major obstacles toward clinical translation remain. Among them, the inability to recapitulate the structure and mechanics of native tissues and the complications associated with integration of artificial and native tissues are long-lasting challenges, calling for new solutions and transdisciplinary efforts.
In this talk, I will present recent progress from my lab at the interaction of materials, mechanics, and bioengineering. I will start with a new bioprinting technology, capable of producing 3D hierarchical cell-laden scaffolds with a unique combination of structural and mechanical properties. Its applications in in vitro cancer model, tissue engineering and microfluidics are discussed. To integrate artificial and native tissues, I will then present bioinspired tough adhesives and multifunctional surgical sutures that achieve unprecedented mechanical and biological functions. Fundamental understanding, computational modeling and practical applications are presented. This talk will highlight the fusion of disciplines such as materials, mechanics, and bioengineering, where new materials and technologies emerge to potentially transform tissue engineering.
Dr. Jianyu Li is Canada Research Chair in Biomaterials and Musculoskeletal Health, Assistant Professor in the Department of Mechanical Engineering, and Associate Member in the Departments of Biomedical Engineering and Surgery at McGill University. He graduated from Zhejiang University and obtained a Ph.D. degree in Mechanical Engineering from Harvard University. He conducted postdoctoral research on biomaterials at the Harvard Wyss Institute. His current research is focused on the design and mechanics of biomaterials for tissue-repair applications. Dr. Li receives the Christophe Pierre Research Excellence Award (Early Career) from McGill University, the Wyss Technology Development Award from Harvard University and is listed in Innovators under 35 China by MIT Technology Review. His work has been covered by the New England Journal of Medicine, JAMA, and many news outlets such as the BBC, the CBC, etc.